Sort by
Previous Page Page 1 of 6 Next Page
  1. Research

    N-acetylcysteine improves antitumoural response of Interferon alpha by NF-kB downregulation in liver cancer cells

    Liver cancer is one of the most common malignancies in the world and at the moment, there is no drug intervention effective for the treatment of liver tumours. Investigate the effect of N-acetylcysteine (NAC),...

    Nelson Alexandre Kretzmann, Eduardo Chiela, Ursula Matte, Norma Marroni and Claudio Augusto Marroni

    Comparative Hepatology 2012 11:4

    Published on: 4 December 2012

  2. Research

    The genetic regulation of the terminating phase of liver regeneration

    After partial hepatectomy (PHx), the liver regeneration process terminates when the normal liver-mass/body-weight ratio of 2.5% has been re-established. To investigate the genetic regulation of the terminating...

    Ingvild E Nygård, Kim E Mortensen, Jakob Hedegaard, Lene N Conley, Trine Kalstad, Christian Bendixen and Arthur Revhaug

    Comparative Hepatology 2012 11:3

    Published on: 20 November 2012

  3. Research

    Protection against Fas-induced fulminant hepatic failure in liver specific integrin linked kinase knockout mice

    Programmed cell death or apoptosis is an essential process for tissue homeostasis. Hepatocyte apoptosis is a common mechanism to many forms of liver disease. This study was undertaken to test the role of ILK i...

    Shashikiran Donthamsetty, Wendy M Mars, Anne Orr, Chuanyue Wu and George K Michalopoulos

    Comparative Hepatology 2011 10:11

    Published on: 21 November 2011

  4. Research

    The effect of cocoa supplementation on hepatic steatosis, reactive oxygen species and LFABP in a rat model of NASH

    Non alcoholic steatohepatitis is hypothesised to develop via a mechanism involving fat accumulation and oxidative stress. The current study aimed to investigate if an increase in oxidative stress was associate...

    Mile Janevski, Kiriakos N Antonas, Melanie J Sullivan-Gunn, Maree A McGlynn and Paul A Lewandowski

    Comparative Hepatology 2011 10:10

    Published on: 14 November 2011

  5. Case Report

    Autoimmune liver disease - are there spectra that we do not know?

    Autoimmune liver diseases (AILDs) are common leading causes for liver cirrhosis and terminal stage of liver disease. They have variable prevalence among patients with liver disease and have two major clinical ...

    Hind I Fallatah and Hisham O Akbar

    Comparative Hepatology 2011 10:9

    Published on: 12 September 2011

  6. Research

    Evaluation of the effects of a VEGFR-2 inhibitor compound on alanine aminotransferase gene expression and enzymatic activity in the rat liver

    Traditional assessment of drug-induced hepatotoxicity includes morphological examination of the liver and evaluation of liver enzyme activity in serum. The objective of the study was to determine the origin of...

    Carmen Fuentealba, Monali Bera, Bart Jessen, Fred Sace, Greg J Stevens, Dusko Trajkovic, Amy H Yang and Winston Evering

    Comparative Hepatology 2011 10:8

    Published on: 17 August 2011

  7. Case Report

    Situs inversus totalis and secondary biliary cirrhosis: a case report

    Situs inversus totalis is is a congenital anomaly associated with various visceral abnormalities, but there is no data about the relationship between secondary biliary cirrhosis and that condition. We here pre...

    Hacı Mehmet Sökmen, Kamil Özdil, Turan Çalhan, Abdurrahman Şahin, Ebubekir Şenateş, Resul Kahraman, Adil Niğdelioğlu and Ebru Zemheri

    Comparative Hepatology 2011 10:5

    Published on: 3 August 2011

  8. Research

    Hepatic expression of multidrug resistance protein 2 in biliary atresia

    Biliary atresia (BA) is an idiopathic inflammatory obliterative cholangiopathy of neonates, leading to progressive biliary cirrhosis. Hepatoportoenterostomy (Kasai procedure) can cure jaundice in 30% to 80% of...

    Keita Terui, Takeshi Saito, Tomoro Hishiki, Yoshiharu Sato, Tetsuya Mitsunaga and Hideo Yoshida

    Comparative Hepatology 2011 10:6

    Published on: 3 August 2011

  9. Research

    Characterization of chronic HCV infection-induced apoptosis

    To understand the complex and largely not well-understood apoptotic pathway and immune system evasion mechanisms in hepatitis C virus (HCV)-associated hepatocellular carcinoma (HCC) and HCV associated chronic ...

    Abdel-Rahman N Zekri, Abeer A Bahnassy, Mohamed M Hafez, Zeinab K Hassan, Mahmoud Kamel, Samah A Loutfy, Ghada M Sherif, Abdel-Rahman El-Zayadi and Sayed S Daoud

    Comparative Hepatology 2011 10:4

    Published on: 23 July 2011

  10. Research

    Effects of ischemic pre- and postconditioning on HIF-1α, VEGF and TGF-β expression after warm ischemia and reperfusion in the rat liver

    Ischemic pre- and postconditioning protects the liver against ischemia/reperfusion injuries. The aim of the present study was to examine how ischemic pre- and postconditioning affects gene expression of hypoxi...

    Anders R Knudsen, Anne-Sofie Kannerup, Henning Grønbæk, Kasper J Andersen, Peter Funch-Jensen, Jan Frystyk, Allan Flyvbjerg and Frank V Mortensen

    Comparative Hepatology 2011 10:3

    Published on: 19 July 2011

  11. Research

    Characterization of Kupffer cells in livers of developing mice

    Kupffer cells are well known macrophages of the liver, however, the developmental characteristics of Kupffer cells in mice are not well understood. To clarify this matter, the characteristics of Kupffer macrop...

    Bryan G Lopez, Monica S Tsai, Janie L Baratta, Kenneth J Longmuir and Richard T Robertson

    Comparative Hepatology 2011 10:2

    Published on: 12 July 2011

  12. Research

    Expression of hepatocytic- and biliary-specific transcription factors in regenerating bile ducts during hepatocyte-to-biliary epithelial cell transdifferentiation

    Under compromised biliary regeneration, transdifferentiation of hepatocytes into biliary epithelial cells (BEC) has been previously observed in rats, upon exposure to BEC-specific toxicant methylene dianiline ...

    Pallavi B Limaye, William C Bowen, Anne Orr, Udayan M Apte and George K Michalopoulos

    Comparative Hepatology 2010 9:9

    Published on: 2 December 2010

  13. Research

    Adoptive transfer of splenocytes to study cell-mediated immune responses in hepatitis C infection using HCV transgenic mice

    Hepatitis C virus (HCV) is a major cause of chronic hepatitis and a health problem affecting over 170 million people around the world. We previously studied transgenic mice that express HCV Core, Envelope 1 an...

    Turaya Naas, Masoud Ghorbani, Catalina Soare, Nicole Scherling, Rudy Muller, Peyman Ghorbani and Francisco Diaz-Mitoma

    Comparative Hepatology 2010 9:7

    Published on: 20 August 2010

  14. Research

    Daytime food restriction alters liver glycogen, triacylglycerols, and cell size. A histochemical, morphometric, and ultrastructural study

    Temporal restriction of food availability entrains circadian behavioral and physiological rhythms in mammals by resetting peripheral oscillators. This entrainment underlies the activity of a timing system, dif...

    Mauricio Díaz-Muñoz, Olivia Vázquez-Martínez, Adrián Báez-Ruiz, Gema Martínez-Cabrera, María V Soto-Abraham, María C Ávila-Casado and Jorge Larriva-Sahd

    Comparative Hepatology 2010 9:5

    Published on: 23 February 2010

  15. Research

    Keratin 19 marks poor differentiation and a more aggressive behaviour in canine and human hepatocellular tumours

    The expression of Keratin 19 (K19) was reported in a subset of hepatocellular carcinomas (HCCs). K19 positive HCCs are associated with an increased malignancy compared to K19 negative HCCs. No suitable mouse m...

    Renee GHM van Sprundel, Ted SGAM van den Ingh, Valeer J Desmet, Azeam Katoonizadeh, Louis C Penning, Jan Rothuizen, Tania Roskams and Bart Spee

    Comparative Hepatology 2010 9:4

    Published on: 18 February 2010

  16. Research

    Chlamydia trachomatisgrowth inhibition and restoration of LDL-receptor level in HepG2 cells treated with mevastatin

    Perihepatitis is rare but consistently occurring extragenital manifestation of untreated Chlamydia trachomatis infection. Despite of possible liver involvement in generalized C. trachomatis infection, the ability...

    Yuriy K Bashmakov, Nailya A Zigangirova, Yulia P Pashko, Lidia N Kapotina and Ivan M Petyaev

    Comparative Hepatology 2010 9:3

    Published on: 28 January 2010

  17. Research

    Increased sinusoidal flow is not the primary stimulus to liver regeneration

    Hemodynamic changes in the liver remnant following partial hepatectomy (PHx) have been suggested to be a primary stimulus in triggering liver regeneration. We hypothesized that it is the increased sinusoidal f...

    Kim E Mortensen, Lene N Conley, Ingvild Nygaard, Peter Sorenesen, Elin Mortensen, Christian Bendixen and Arthur Revhaug

    Comparative Hepatology 2010 9:2

    Published on: 20 January 2010

  18. Research

    Serum levels of soluble Fas, soluble tumor necrosis factor-receptor II, interleukin-2 receptor and interleukin-8 as early predictors of hepatocellular carcinoma in Egyptian patients with hepatitis C virus genotype-4

    Liver disease progression from chronic hepatitis C virus (HCV) infection to hepatocellular carcinoma (HCC) is associated with an imbalance between T-helper 1 and T-helper 2 cytokines. Evaluation of cytokines a...

    Abdel-Rahman N Zekri, Hanaa M Alam El-Din, Abeer A Bahnassy, Naglaa A Zayed, Waleed S Mohamed, Suzan H El-Masry, Sayed K Gouda and Gamal Esmat

    Comparative Hepatology 2010 9:1

    Published on: 5 January 2010

Previous Page Page 1 of 6 Next Page