Figure 6
From: Low affinity glucocorticoid binding site ligands as potential anti-fibrogenics
Screening for inhibitors of trans-differentiation in rat and human HSCs – Part 2. Photomicrographs of human HSCs at day 12 of culture with the indicated treatment (a); levels of expression of α-smooth muscle actin (α-sma) (b) and levels of expression of fibrogenic marker mRNA transcripts in human HSCs after treatment selected compounds for 19 days. Data are the mean and standard deviation relative transcript level from 3 separate treatments on cells from the same donor, typical of at least 3 separate donors (c).