Distribution of hepatitis C virus genotypes in patients infected by different sources and its correlation with clinical and virological parameters: a preliminary study

Kabir, Ali; Alavian, Seyed-Moayed; Keyvani, Hussein

doi:10.1186/1476-5926-5-4

Table 1 Presentation of the 156 Iranian patients in relation to HCV-genotype.

From: Distribution of hepatitis C virus genotypes in patients infected by different sources and its correlation with clinical and virological parameters: a preliminary study

Presentation of patients	HCV-genotype					Sig.
	1a (N = 59)	1b (N = 26)	1a & 1b (N = 2)	3a^c(N = 45)	4 (N = 2)
Age (years) ^a	37.5 ± 1.7	38.7 ± 2.4	46.5 ± 2.5	39.6 ± 1.8	46.5 ± 3.5	NS^d
Male/Female (%male)	47/12 (79.7)	19/7 (73.1)	2/0 (100)	39/7 (84.8)	1/1 (50)	NS
Transmission of HCV
*Post-transfusional*	24 (42.1)	10 (17.5)	1 (1.8)	15 (26.3)	0	NS
*IVDA*	18 (40)	5 (11.1)	0	18 (40)	0	NS
*Sexual*	16 (36.4)	6 (13.6)	0	19 (43.2)	0	NS
*Hemodialysis*	7 (36.8)	2 (10.5)	1 (5.3)	4 (21.1)	2 (10.5)	0.001
*Hemophilia*	3 (60)	0	0	2 (40)	0	NS
*Thalassemia*	5 (55.6)	2 (22.2)	0	1 (11.1)	0	NS
*Inmate*	12 (34.3)	2 (5.7)	0	17 (48.6)	0	0.041
*Travel abroad*	9 (40.9)	3 (13.6)	1 (4.5)	7 (31.8)	0	NS
*Hejamat* ^e	8 (25)	6 (18.8)	1 (3.1)	14 (43.8)	1 (3.1)	NS
*Other risk factors*	10 (34.5)	5 (17.2)	0	7 (24.1)	0	NS
Cirrhosis	7	5	0	7	0	NS
HAI ^{a, b}	7.8 ± 1.1	10 ± 1.3	3 ± .0	8.6 ± 1.1	12 ± .0	NS
AST (U/L)	59.9 ± 5.8	67.8 ± 9.5	48.5 ± 12.5	71.1 ± 7.5	91.5 ± 75.5	NS
ALT (U/L)	73.6 ± 7.2	94.1 ± 14.8	40 ± 5	94.7 ± 10	139.5 ± 113.5	NS
WBC (/ml)	6866 ± 501	7405 ± 578	7000 ± 500	6993 ± 366	6500 ± 500	NS
PLT (/ml)	227281 ± 20455	194560 ± 10377	314000 ± .0	217391 ± 12168	244500 ± 22500	NS
Hgb (g/dl)	14.1 ± .33	14.5 ± .42	14.2 ± 2.6	14.5 ± .32	14.4 ± 2.2	NS
FBS (mg/dl)	105.4 ± 6.8	102.7 ± 9.4	97 ± 11	102.7 ± 8	106.5 ± 1.5	NS
TG (mg/dl)	142.3 ± 11.2	123.2 ± 10.7	176 ± 110	101.1 ± 6.9	215 ± 143	.016
Cholesterol (mg/dl)	159.7 ± 6.4	173.8 ± 9.1	185 ± .0	140.8 ± 7.3	186 ± 73	NS
Serum albumin (g/dl)	3.9 ± .08	4.1 ± .13	3.6 ± .25	4.1 ± .1	-	NS
Serum protein (g/dl)	7.4 ± .11	7.6 ± .18	6.4 ± .65	7.8 ± .13	-	.034
Serum iron	132.6 ± 13.8	118.4 ± 18.8	-	81.1 ± 8.8	110 ± .0	.024
Weight (Kg)	71.6 ± 1.9	70.5 ± 3.4	75.5 ± 14.5	72.7 ± 1.9	84.5 ± 2.5	NS
Height (cm)	170.8 ± 1.3	167.3 ± 2.1	169.5 ± 1.5	171.8 ± 1.2	163 ± 11	NS

^a Mean ± SE; ^b Histological activity index; ^c One patient had a mixed infection (3a(β)/1a); ^d Not significant; ^e A procedure in Iranian traditional medicine done by making shallow cuts on the trunk (upper back) and producing a suction effect that results in drawing blood from cuts (less than 100 cc). It is usually done by a non-physician, using non-standard instruments (done for healing or cure purposes). It is also named "cupping".

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Comparative Hepatology