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Figure 1 | Comparative Hepatology

Figure 1

From: 3-D structure of extracellular matrix regulates gene expression in cultured hepatic stellate cells to induce process elongation

Figure 1

Alteration in cell shape (a) and gene expression (b) by ECM in cultured HSCs. Fig. 1a shows HSC shape after culturing on polystyrene surface (A), on type I collagen gel (B), in type I collagen gel (C), or on Matrigel (D). Fig. 1b indicates a representative PCR-DD showing differentially expressed transcripts in HSCs cultured on polystyrene (1), on type I collagen gel (2), or in type I collagen gel (3). Black and open arrowheads indicate the PCR products derived from down- and up-regulated transcripts, respectively, by extracellular type I collagen.

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