Comparative Hepatology

Table 3 Effect of ethanol and thalidomide on LPS-induced increases in intracellular Ca²⁺ and TNF-alpha production in isolated Kupffer cells.

From: Thalidomide Prevents Alcoholic Liver Injury in Rats Through Inhibition of Kupffer Cell Sensitization

	[Ca²⁺]_i (nM)	TNF-alpha(pg/ml)
LPS (100 ng/ml)	85 – 4	559 – 71
Thalido 4 weeks + LPS	92 – 6	578 – 77
Ethanol 4 weeks + LPS	227 – 26*	1104 – 110*
Ethanol + Thalido 4 weeks + LPS	83 – 4**	625 – 72**

* p < 0.05 vs. control, ** p < 0.05 vs. 4 weeks of ethanol.

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