Figure 3
From: The effect of cytochalasin B – Loaded liposomes on the ultrastructure of the liver sieve
Fluorescence- and SEM images of LSECs in vitro (A-D) and in vivo (E-F) treated with Aco-HSA (A, C, E) (control) and with Aco-HSA CB-loaded liposomes (B, D, F) at a CB concentration of 0.025 microgram/ml for two hours. No signs of F-actin disruption could be observed in both conditions (A-B) (compare with Fig. 1A) and fenestral number remained unchanged (C-D) (compare with Fig. 1B). Nucleus (N), Fenestrae (arrow). (E-F) SEM images of the sinusoidal lumen (S) and parenchymal cells (P). Fenestrae (arrow). No significance difference in the number of fenestrae could be determined between the control (E) and rats injected with Aco-HSA CB-loaded liposomes (F). Bars A-B = 15 –m; C-D = 2 –m; E-F = 1 –m.