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Table 3 GSH/GSSG levels in hepatocytes after in vivo treatment with Pb(NO3)2, GdCl3 or with 24 hours pretreatment of GdCl3 before exposure to Pb(NO3)2.*

From: Kupffer cells promote lead nitrate-induced hepatocyte apoptosis via oxidative stress

Days Untreated PbNO3 GdCl3 GdCl3/PbNO3
  16.05/0.20 {3}    
1   13.34/2.93 {3} 14.90/6.29 {2} 8.15/2.35 {2}
3   3.20/2.13 {10} 5.86/5.39 {10} 11.23/2.83 {6}
5   3.49/1.36 {39} 5.90/3.43 {15} 10.24/6.11 {18}
15   2.74/0.64 {20} 10.18/0.61 {10} 10.18/6.61 {10}
  1. * The values are given as total glutathione intracellular GSH/GSSG nmol/mg protein. The relative apoptotic percentages are reported in square brackets. Standard deviations did not exceed 5%. For each point 4 animals have been used.