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Table 5 Correlation between gene expression and clinicopathological features in CH patients

From: Characterization of chronic HCV infection-induced apoptosis

Variable

N = 34 (%)

Bak

N = 16 (%)

Fas

N = 19 (%)

FasL

N = 16 (%)

Bcl-2

N = 20 (%)

Age (mean ± SD)

    

44 ± 9.8

    

≤ 47: 18 (53)

8 (44)

13 (72) #

8 (44)

9 (50)

> 47: 16 (47)

8 (50)

6 (38)

8 (50)

11 (69)

Gender

    

M: 31 (91)

13 (41)

17 (55)

15 (48)

18 (58)

F: 3 (8)

3 (100) #

2 (67) #

1 (33)

2 (66)

Steatosis

    

Absent: (10)

3 (30)

3 (30)

2 (20)

4 (40)

Minimal: (14)

7 (50)

9 (64)

4 (29)

10 (71)

Moderate: (7)

4 (57)

5 (71)

7 (100)

5 (71)

Marked: (3)

2 (67)

2 (67)

3 (100)

1 (33)

Necrosis

    

Absent: (26)

12 (46)

13 (50)

9 (35)

16 (62)

Minimal: (8)

4 (50)

6 (75)

7 (88) #

4 (50)

Necro-inflammation

    

Absent: (10)

4 (40)

5 (50)

0 (0)

3 (30)

Minimal: (15)

8 (53)

9 (60)

8 (53)

11 (73)

Moderate: (9)

4 (44)

5 (56)

8 (89)

6 (67)

Cirrhosis

    

Present:12 (35)

6 (50)

6 (50)

6(50)

9 (75) #

Absent: 22 (65)

10 (45%)

13 (59)

10(45)

11 (50)

Hepatitis grade

    

I &II: (26)

11 (42)

12 (46)

9 (35)

15 (58)

III&IV: (8)

5 (63)

7 (88) #

7 (88) #

5 (63)

Hepatitis stage

    

I &II: (25)

12 (48)

13 (52)

8 (32)

16 (64)

III &IV: (9)

4 (44)

6 (67)

8 (89) #

4 (44)

  1. Bcl-xL was not expressed in any of the studied CH cases. # significantly difference (p < 0.005).