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Table 5 Correlation between gene expression and clinicopathological features in CH patients

From: Characterization of chronic HCV infection-induced apoptosis

Variable
N = 34 (%)
Bak
N = 16 (%)
Fas
N = 19 (%)
FasL
N = 16 (%)
Bcl-2
N = 20 (%)
Age (mean ± SD)     
44 ± 9.8     
≤ 47: 18 (53) 8 (44) 13 (72) # 8 (44) 9 (50)
> 47: 16 (47) 8 (50) 6 (38) 8 (50) 11 (69)
Gender     
M: 31 (91) 13 (41) 17 (55) 15 (48) 18 (58)
F: 3 (8) 3 (100) # 2 (67) # 1 (33) 2 (66)
Steatosis     
Absent: (10) 3 (30) 3 (30) 2 (20) 4 (40)
Minimal: (14) 7 (50) 9 (64) 4 (29) 10 (71)
Moderate: (7) 4 (57) 5 (71) 7 (100) 5 (71)
Marked: (3) 2 (67) 2 (67) 3 (100) 1 (33)
Necrosis     
Absent: (26) 12 (46) 13 (50) 9 (35) 16 (62)
Minimal: (8) 4 (50) 6 (75) 7 (88) # 4 (50)
Necro-inflammation     
Absent: (10) 4 (40) 5 (50) 0 (0) 3 (30)
Minimal: (15) 8 (53) 9 (60) 8 (53) 11 (73)
Moderate: (9) 4 (44) 5 (56) 8 (89) 6 (67)
Cirrhosis     
Present:12 (35) 6 (50) 6 (50) 6(50) 9 (75) #
Absent: 22 (65) 10 (45%) 13 (59) 10(45) 11 (50)
Hepatitis grade     
I &II: (26) 11 (42) 12 (46) 9 (35) 15 (58)
III&IV: (8) 5 (63) 7 (88) # 7 (88) # 5 (63)
Hepatitis stage     
I &II: (25) 12 (48) 13 (52) 8 (32) 16 (64)
III &IV: (9) 4 (44) 6 (67) 8 (89) # 4 (44)
  1. Bcl-xL was not expressed in any of the studied CH cases. # significantly difference (p < 0.005).