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Table 3 Comet assay on peripheral blood and liver tissues from mice subjected to hypoxia.

From: Hepatic oxidative stress in an animal model of sleep apnoea: effects of different duration of exposure

 

SIH

IH-35

Tissue

Damage indexa

Damage frequencyb

Damage index

Damage frequency

Blood

15.3 ± 4.4

7.6 ± 1.3

19.3 ± 4.1

8.0 ± 1.4

Liver

38.1 ± 5.1

14.8 ± 1.8

114.7 ± 32.3**

43.2 ± 11.3**

  1. Data are presented as mean ± standard error (n = 6 animals/group). SIH: sham intermittent hypoxia group; IH-35: intermittent hypoxia for 35 days. a, Damage index: can range from 0 (completely undamaged, 100 cells × 0) to 400 (with maximum damage, 100 × 4). b, Damage frequency: calculated based on the number of cells with tails versus those with no tail. **, p < 0.01, statistically significant difference from sham intermittent hypoxia group (t-test).
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Comparative Hepatology

ISSN: 1476-5926