Skip to main content

Table 4 Laboratory analyzers and biochemical methods

From: A prospective assessment of the inter-laboratory variability of biochemical markers of fibrosis (FibroTest) and activity (ActiTest) in patients with chronic liver disease

  LAB 1 (Reference center) LAB 2 LAB 3
α2-macroglobulin    
   Analyzer BN2 BN2 BN2
   Method Nephelemetry Nephelemetry Nephelemetry
Haptoglobin    
   Analyzer BN2 BN2 BN2
   Method Nephelemetry Nephelemetry Nephelemetry
Apolipoprotein A1    
   Analyzer BN2 RXL RXL
   Method Nephelemetry Turbidimetry Turbidimetry
Total bilirubin    
   Analyzer Modular RXL RXL
   Method Diazoreaction Diazoreaction Diazoreaction
Aminotransferase    
   Analyzer Modular RXL RXL
   Method IFCC Pyridoxal IFCC Pyridoxal IFCC Pyridoxal
γ-glutamyl transpeptidase    
   Analyzer Modular RXL RXL
   Method Szasz standardized Szasz Szasz
  LAB 4 LAB 5 LAB 6
α 2 -macroglobulin    
   Analyzer BN2 BN2 BN2
   Method Nephelemetry Nephelemetry Nephelemetry
Haptoglobin    
   Analyzer BN2 Advia1650 Integra 800
   Method Nephelemetry Turbidimetry Turbidimetry
Apolipoprotein A1    
   Analyzer Hitachi 911 Advia 1650 Integra 800
   Method Turbidimetry Turbidimetry Turbidimetry
Total bilirubin    
   Analyzer Hitachi 911 Advia 1650 Integra 800
   Method Diazoreaction Diazoreaction Diazoreaction
Aminotransferase    
   Analyzer Hitachi 911 Advia1650 Integra 800
   Method IFCC Pyridoxal IFCC IFCC
γ-glutamyl transpeptidase    
   Analyzer Hitachi 911 Advia1650 Integra 800
   Method Szasz standardized Szasz Szasz standardized
  LAB 7 LAB 10 LAB 11
α 2 -macroglobulin    
   Analyzer BN2 BN2 Immage
   Method Nephelemetry Nephelemetry Nephelemetry
Haptoglobin    
   Analyzer BN2 BN2 Immage
   Method Nephelemetry Nephelemetry Nephelemetry
Apolipoprotein A1    
   Analyzer Advia 1650 CX5 Immage
   Method Turbidimetry Turbidimetry Nephelemetry
Total bilirubin    
   Analyzer Advia CX7 Vitros 250
   Method Diazoreaction Diazoreaction Diazoreaction
Aminotransferase    
   Analyzer Advia CX7 Vitros 250
   Method IFCC IFCC IFCC Pyrydoxal
γ-glutamyl transpeptidase    
   Analyzer Advia 1650 CX7 Vitros 250
   Method Szasz Szasz Szasz
  1. BN2, RXL, Vitros 250: Dade Behring, Marburg, Germany. Hitachi 911, Integra 800: Modular DP Roche Diagnostics, Mannheim, Germany. Immage, CX5, CX7: Beckman Coulter, Brea, California, USA. Advia 1650: Bayer Diagnostics, Tarrytown, New Jersey, USA. IFCC: International Federation of Clinical Chemistry.