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  1. It has been suggested that the elastic network plays an important role in the tissue response to mechanical stress. The components of the elastic network have been poorly studied in liver diseases. Therefore, ...

    Authors: Sébastien Lepreux, Alexis Desmouliere, Jean Rosenbaum, Charles Balabaud and Paulette Bioulac-Sage
    Citation: Comparative Hepatology 2004 3(Suppl 1):S57

    This article is part of a Supplement: Volume 3 Supplement 1

  2. Authors: Eiji Matsumoto, Harushige Nakatsukasa, Kazuhiro Nouso, Shin-ichiro Nakamura, Mayumi Suzuki, Yoshiyuki Kobayashi, Masayuki Uemura, Syuichiro Sato, Ei-ichiro Yumoto, Junko Yokoyama, Sou Tsuboi, Hironori Tanaka, Yoshiataka Takuma, Tatsuya Fujikawa and Yasushi Shiratori
    Citation: Comparative Hepatology 2004 3(Suppl 1):S51

    This article is part of a Supplement: Volume 3 Supplement 1

  3. Vascular injury and accumulation of red blood cells in the space of Disse (hemorrhage) is a characteristic feature of acetaminophen hepatotoxicity. However, the mechanism of nonparenchymal cell injury is uncle...

    Authors: Tamara R Knight and Hartmut Jaeschke
    Citation: Comparative Hepatology 2004 3(Suppl 1):S46

    This article is part of a Supplement: Volume 3 Supplement 1

  4. We investigated activation mechanisms of hepatic stellate cells (HSCs) that are known to play pivotal roles in the regeneration process after 70% partial hepatectomy (PHx). Parenchymal liver cells (PLCs) and n...

    Authors: Ayako Mabuchi, Ian Mullaney, Philip Sheard, Paul Hessian, Arthur Zimmermann, Haruki Senoo and Antony M Wheatley
    Citation: Comparative Hepatology 2004 3(Suppl 1):S29

    This article is part of a Supplement: Volume 3 Supplement 1

  5. Authors: Peter AG McCourt, Berit Hansen, Dmitri Svistuonov, Sophie Johansson, Paola Longati, Kai Schledzewski, Julia Kzhyshkowska, Sergij Goerdt, Staffan Johansson and B–rd Smedsr–d
    Citation: Comparative Hepatology 2004 3(Suppl 1):S24

    This article is part of a Supplement: Volume 3 Supplement 1

  6. Hepatic stellate cells (HSC) changed their morphology and function including production of matrix metalloproteinases (MMPs) in response to extracellular matrix (ECM) component used as a substratum in culture. ...

    Authors: Da-Ren Wang, Mitsuru Sato, Takeya Sato, Naosuke Kojima, Nobuyo Higashi and Haruki Senoo
    Citation: Comparative Hepatology 2004 3(Suppl 1):S20

    This article is part of a Supplement: Volume 3 Supplement 1

  7. Authors: Haruki Senoo, Kenjiro Wake, Heidi L Wold, Nobuyo Higashi, Katsuyuki Imai, Jan Øivind Moskaug, Naosuke Kojima, Mitsutaka Miura, Takeya Sato, Mitsuru Sato, Norbert Roos, Trond Berg, Kaare R Norum and Rune Blomhoff
    Citation: Comparative Hepatology 2004 3(Suppl 1):S18

    This article is part of a Supplement: Volume 3 Supplement 1

  8. We examined the liver of adult polar bears, arctic foxes, and rats by gold chloride staining, fluorescence microscopy for the detection of autofluorescence of vitamin A, hematoxylin-eosin staining, staining wi...

    Authors: Nobuyo Higashi, Katsuyuki Imai, Mitsuru Sato, Takeya Sato, Naosuke Kojima, Mitsutaka Miura, Heidi L Wold, Jan Øivind Moskaug, Trond Berg, Kaare R Norum, Norbert Roos, Kenjiro Wake, Rune Blomhoff and Haruki Senoo
    Citation: Comparative Hepatology 2004 3(Suppl 1):S16

    This article is part of a Supplement: Volume 3 Supplement 1

  9. Emerging evidence has suggested a critical role of leptin in hepatic inflammation and fibrogenesis, however, the precise mechanisms underlying the profibrogenic action of leptin in the liver has not been well ...

    Authors: Kenichi Ikejima, Tie Lang, Yan-Jun Zhang, Shunhei Yamashina, Hajime Honda, Mutsuko Yoshikawa, Miyoko Hirose, Nobuyuki Enomoto, Tsuneo Kitamura, Yoshiyuki Takei and Nobuhiro Sato
    Citation: Comparative Hepatology 2004 3(Suppl 1):S12

    This article is part of a Supplement: Volume 3 Supplement 1

  10. Activation of Hepatic stellate cells (HSC) in fibrogenesis involves distinct morphological and biochemical changes. This activation requires the coordinated changes in activity of several transcription factors...

    Authors: Saswati Hazra, Takeo Miyahara, Richard A Rippe and Hidekazu Tsukamoto
    Citation: Comparative Hepatology 2004 3(Suppl 1):S7

    This article is part of a Supplement: Volume 3 Supplement 1

  11. The role of adenosine and ATP in the regulation of hepatic arterial blood flow in the "buffer response" was studied in vitro and in a new in vivo model in the rabbit. The model achieves portal-systemic diversion ...

    Authors: Dominic J Browse, Robert T Mathie, Irving S Benjamin and Barry Alexander
    Citation: Comparative Hepatology 2003 2:9
  12. Apoptosis and its modulation are crucial factors for the maintenance of liver health, allowing hepatocytes to die without provoking a potential harmful inflammatory response through a tightly controlled and re...

    Authors: Patrizia Pagliara, Emanuela C Carlà, Sonia Caforio, Alfonsina Chionna, Silvia Massa, Luigi Abbro and Luciana Dini
    Citation: Comparative Hepatology 2003 2:8
  13. The typical lesion of focal nodular hyperplasia (FNH) is a benign tumor-like mass characterized by hepatocytic nodules separated by fibrous bands. The solitary central artery with high flow and the absent port...

    Authors: Sébastien Lepreux, Christophe Laurent, Charles Balabaud and Paulette Bioulac-Sage
    Citation: Comparative Hepatology 2003 2:7
  14. We report our experience of the simultaneous occurrence of adenoma and focal nodular hyperplasia (FNH). Liver cell adenoma together with FNH was found in five out of 30 cases of "multiple benign hepatocytic no...

    Authors: Christophe Laurent, Hervé Trillaud, Sébastien Lepreux, Charles Balabaud and Paulette Bioulac-Sage
    Citation: Comparative Hepatology 2003 2:6
  15. Recent advances in molecular biology have made possible the identification of genetic defects responsible for Wilson's disease, Indian childhood cirrhosis and copper toxicosis in Long Evans Cinnamon rats, toxi...

    Authors: I Carmen Fuentealba and Enrique M Aburto
    Citation: Comparative Hepatology 2003 2:5
  16. The oocyte is the starting point for a new generation. Most of the machinery for DNA and protein synthesis needed for the developing embryo is made autonomously by the fertilized oocyte. However, in fish and i...

    Authors: Augustine Arukwe and Anders Goksøyr
    Citation: Comparative Hepatology 2003 2:4
  17. Peroxisome proliferator activated receptors (PPARs) are a family of related receptors implicated in a diverse array of biological processes. There are 3 main isotypes of PPARs known as PPARα, PPARβ and PPARγ a...

    Authors: Eric Boitier, Jean-Charles Gautier and Ruth Roberts
    Citation: Comparative Hepatology 2003 2:3
  18. In cirrhotic livers, the balance of vasoactive substances is in favour of vasoconstrictors with relatively insufficient nitric oxide. Endothelial dysfunction has been documented in cirrhotic rat livers leading...

    Authors: Marc Van de Casteele, Jos F van Pelt, Frederik Nevens, Johan Fevery and Jürg Reichen
    Citation: Comparative Hepatology 2003 2:2
  19. Numerous studies in rats and a few other mammalian species, including man, have shown that the sinusoidal cells constitute an important part of liver function. In the pig, however, which is frequently used in ...

    Authors: Geir I Nedredal, Kjetil H Elvevold, Lars M Ytrebø, Randi Olsen, Arthur Revhaug and Bård Smedsrød
    Citation: Comparative Hepatology 2003 2:1
  20. Biochemical markers for liver fibrosis (FibroTest) and necroinflammatory features (ActiTest) are an alternative to liver biopsy in patients with chronic hepatitis C. Our aim was to assess the inter-laboratory ...

    Authors: Philippe Halfon, Françoise Imbert-Bismut, Djamila Messous, Gilles Antoniotti, Didier Benchetrit, Philippe Cart-Lamy, Gilles Delaporte, Danièle Doutheau, Théo Klump, Michel Sala, Didier Thibaud, Elisabeth Trepo, Dominique Thabut, Robert P Myers and Thierry Poynard
    Citation: Comparative Hepatology 2002 1:3
  21. Hepatic natural killer (NK) cells, the most cytotoxic cells of the natural occurring NK cells, are located in the liver sinusoids and are thus in a strategic position to kill arriving metastasising tumour cell...

    Authors: Dianzhong Luo, David Vermijlen, Peter JK Kuppen and Eddie Wisse
    Citation: Comparative Hepatology 2002 1:2