Comparative Hepatology

Table 4 ROC curve values for sTNFR-II and IL-8 in PNALT and HCC patients

From: Serum levels of soluble Fas, soluble tumor necrosis factor-receptor II, interleukin-2 receptor and interleukin-8 as early predictors of hepatocellular carcinoma in Egyptian patients with hepatitis C virus genotype-4

ROC values	sTNF-RII ≥ 398	IL-8 ≥ 345	TNFR-II ≥ 398 or IL-8 <290
Sensitivity	73.3%	96.7%	100%
Specificity	88.2%	76.5%	70.6%
AUC	0.849	0.588	0.794
NPV	65.2%	92.2%	100%
PPV	91.7%	87.9%	85.7%

ROC - receiving operating characteristic; AUC - area under the curve; NPV - negative predictive value; PPV - positive predictive value; PNALT: Chronic hepatitis C with persistent normal alanine aminotrasferase. HCC: hepatocellular carcinoma.

Back to article page