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Table 2 Serum levels of sFas, sTNFR-II, sIL-2R and IL-8 in the different study groups.

From: Serum levels of soluble Fas, soluble tumor necrosis factor-receptor II, interleukin-2 receptor and interleukin-8 as early predictors of hepatocellular carcinoma in Egyptian patients with hepatitis C virus genotype-4

Cytokines
(pg/ml)
Control PNALT CLD HCC p-value
sFas 316 ± 62.5b 605.82 ± 304ab 814.94 ± 362a 762.18 ± 437a < 0.001
sTNF-RII 375.26 ± 58.4ab 268.58 ± 129b 315.27 ± 133.5b 480.16 ± 154.4a < 0.001
sIL-2Rα 639.84 ± 78.7b 710.10 ± 422b 845.38 ± 385.2ab 1372.58 ± 779.6a 0.001
IL-8 345.84 ± 75.6a 350.7 ± 53.6a 352.33 ± 98.3a 228.61 ± 51.1b < 0.001
  1. Values are expressed as mean ± SD. Groups with similar letters are not statistically different. A p-value < 0.05 was considered significant; PNALT: chronic hepatitis C with persistent normal alanine aminotrasferase; CLD: chronic liver disease; HCC: hepatocellular carcinoma.