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Table 1 Patients characteristics and log-HCV titer among the different study groups

From: Serum levels of soluble Fas, soluble tumor necrosis factor-receptor II, interleukin-2 receptor and interleukin-8 as early predictors of hepatocellular carcinoma in Egyptian patients with hepatitis C virus genotype-4

Variables

Control (9)

PNALT (17)

CLD (32)

HCC (30)

p-value

M/W

7/2

12/5

24/8

25/5

< 0.001

Age (years): Mean ± SD

50.9 ± 4.6b

35.1 ± 11.5c

43.4 ± 8.7b

60.7 ± 8.3a

< 0.001

Log HCV-titer

<615*

10.9 ± 3.2a

9.9 ± 4.1a

5.2 ± 4.7b

< 0.001

  1. Groups with similar letters are not different statistically. A p-value < 0.05 was considered significant. M/W: Men/Women; PNALT: chronic hepatitis C with persistent normal alanine aminotrasferase; CLD: chronic liver disease; HCC: hepatocellular carcinoma. *All cases were under detection limit (<615 IU/ml) and so they were not included in the statistical analysis (Kruskal-Wallis ANOVA).