TY - JOUR AU - Jacobs, Frank AU - Wisse, Eddie AU - De Geest, Bart PY - 2009 DA - 2009/07/13 TI - Early effect of a single intravenous injection of ethanol on hepatic sinusoidal endothelial fenestrae in rabbits JO - Comparative Hepatology SP - 4 VL - 8 IS - 1 AB - It has been postulated that ethanol affects hepatic sinusoidal and perisinusoidal cells. In the current experimental study, we investigated the early effect of a single intravenous dose of ethanol on the diameter of liver sinusoidal endothelial fenestrae in New Zealand White rabbits. The diameter of fenestrae in these rabbits is similar to the diameter found in humans with healthy livers. The effect of ethanol on the size of fenestrae was studied using transmission electron microscopy, because plastic embedding provides true measures for the diameter of fenestrae. SN - 1476-5926 UR - https://doi.org/10.1186/1476-5926-8-4 DO - 10.1186/1476-5926-8-4 ID - Jacobs2009 ER -