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Table 1 Characteristics of the patients.

From: A new parameter using serum lactate dehydrogenase and alanine aminotransferase level is useful for predicting the prognosis of patients at an early stage of acute liver injury: A retrospective study

 

Alive

LT or Death

Total

p-value

Age

39.4 ± 15.3

48.3 ± 16.3

43.7 ± 16.2

0.0382

Sex (M/F)

10/7

8/8

18/15

0.6109

Ascites (+/-)

2/15

10/6

12/21

0.0025

Encephalopathy (+/-)

2/15

9/7

11/22

0.0067

AST (U/L)

4122.4 ± 3915.1

3587.3 ± 4123.7

3862.9 ± 3963.4

0.5523

ALT (U/L)

3845.5 ± 2932.1

2777.8 ± 2850.6

3327.8 ± 2898.5

0.2275

LDH (U/L)

2668.0 ± 3431.0

2796.1 ± 4093.2

2730.1 ± 3707.3

0.8289

ALP (U/L)

543.7 ± 168.1

509.4 ± 162.5

527.1 ± 163.7

0.9139

γ-GTP (U/L)

293.1 ± 200.0

245.8 ± 249.8

270.2 ± 223.2

0.171

Total bilirubin (mg/dL)

9.1 ± 6.8

14.6 ± 10.0

11.8 ± 8.8

0.0689

Direct bilirubin (mg/dL)

6.1 ± 4.7

9.4 ± 6.9

7.6 ± 6.0

0.1395

Albumin (g/dL)

3.7 ± 0.4

3.3 ± 0.4

3.5 ± 0.4

0.0034

PT-INR

2.19 ± 1.56

3.38 ± 2.29

2.76 ± 2.00

0.0013

Platelet (× 104/μL)

14.9 ± 5.9

11.5 ± 5.9

13.3 ± 6.1

0.0717

Creatinine (mg/dL)

1.14 ± 2.03

1.35 ± 1.61

1.25 ± 1.81

0.5757

Etiology – HAV

3

3

6

0.9811

Etiology – HBV

8

5

13

0.9811

Etiology – Drug

2

1

3

0.9811

Etiology – Wilson

1

1

2

0.9811

Etiology – Unknown

3

6

9

0.9811

MELD score

17.66 ± 9.79

26.69 ± 11.89

22.0 ± 11.6

0.0059

ALT-LDH index 3.0

8

8

16

0.8658

ALT-LDH index ≥ 3.0

9

8

17

0.8658

  1. Values were expressed by mean ± standard deviation. LT: Liver transplantation, GGT: Gamma-glutamyl transferase.