Time-course analysis of LSECs endocytic capacity. Endocytosis of 125I-FSA, a ligand for the LSEC scavenger receptor was monitored at different time points after incubation of cells at normoxic or hyperoxic conditions. Each column represents separate values of cell-associated (lower part) and degraded (upper part) 125I-FSA. Total endocytosis is the result of adding cell associated and degraded ligand (full column size), calculated as percentage of total 125I-FSA added to cultures. Values are means of triplicate measurements. The results are representative data obtained from three independent experiments. Statistical analyses by Student's t-test: *P < 0.05, **P < 0.001.