Figure 2
From: Major HGF-mediated regenerative pathways are similarly affected in human and canine cirrhosis
Quantitative Real-Time PCR of genes involved in regeneration and growth. Expression analysis of acute hepatitis (AH), chronic hepatitis (CH), lobular dissecting hepatitis (LDH), cirrhotic samples (CIRR). HGF expression and detection of the 80 kDa HGF protein is shown in (A). c-MET gene expression and detection of c-MET including phosphorylated (Tyr) form is shown in (B). Relative gene expression data represent mean + SE. A Kolmogorov-Smirnov test was performed to establish a normal distribution and a Levenes test for the homogeneity of variances. All samples included in this study were normally distributed. The statistical significance of differences between diseased and control animals was determined by using the two-sided Dunnetts post-test analysis. A P-value < 0.05 was considered statistically significant. Analysis was performed using SPSS software (SPSS Benelux BV, Gorinchem, the Netherlands).