Figure 3
From: Regeneration in pig livers by compensatory hyperplasia induces high levels of telomerase activity
Telomerase activity three days after surgery. The graphs show median telomerase activity and 1st to 3rd quartile range (error bars) in liver samples from pigs three days after control laparotomy (LT, n = 6) or partial hepatectomy (PH, n = 6) with and without transjugular intrahepatic portosystemic shunt (TIPS, n = 6). Telomerase activity was determined with the real-time quantitative telomeric repeat amplification protocol (RQ-TRAP) and expressed as relative telomerase activity per μg protein (RTA; A), and by the commercially available TeloTAGGG Telomerase PCR ELISAPLUS measuring telomerase activity as total product generated per μg protein (TPG; B). Median RTA values were significantly higher in the PH and PH/TIPS group compared to the LT group (Mann-Whitney U test, P < 0.05 considered significant).