Figure 5From: Endothelin-1 enhances fibrogenic gene expression, but does not promote DNA synthesis or apoptosis in hepatic stellate cellsEffect of ET receptor antagonists on procollagen α1(I) mRNA expression of 1st passage HSC. Cells were stimulated with 10-6 M ET-1 in the absence or presence of the ETAR antagonist BQ123 (10-6 M) or the ETBR antagonist BQ788 (10-6 M) for 48 hours. The mRNA levels were determined by real time quantitative PCR. Results are given as mean ± SD (n = 4). **p < 0.01 vs control, ## p < 0.01 vs ET-1 (10-6 M).Back to article page