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Table 1 Animal and model characteristics

From: Synthesis of acute phase proteins in rats with cirrhosis exposed to lipopolysaccharide

  Bilirubin μmol/l ** ASAT U/l * Liver weight (gram) * Spleen weight (gram)*
Sham 2.7 (0.5) 332 (143) 9.1 (0.8) 0.64 (0.10)
Sham+LPS 3.2 (0.89 345 (156) 8.8 (0.8) 0.76 (0.12)
Cirrhosis 39.5 (3.8) 519 (210) 18.5 (2.8) 1.37 (0.42)
Cirrhosis+LPS 54.2 (7.8) 912 (406) 16.5 (2.4) 1.27 (0.20)
  1. Values are given as: mean (SD). Bilirubin and ASAT (n = 9) and liver/spleen-weights (n = 10) in sham-operated, in sham-operated injected with LPS (bilirubin and ASAT: n = 10, liver/spleen-weights: n = 12), in cirrhotic (bilirubin and ASAT: n = 11, liver/spleen-weights: n = 12) and in cirrhotic animals injected with LPS (n = 9). **Significantly increased (2-way ANOVA, P < 0.001) by both factors i.e. LPS and cirrhosis. *Significantly increased only by cirrhosis (2-way ANOVA, P < 0.001).