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Table 1 Demographics, virological status, and response to treatment of the 20 genotype 1 patients

From: Kinetics of hepatitis C virus RNA load during pegylated interferon alpha-2a and ribavirin treatment in naïve genotype 1 patients

ID

Sex

Age

Genotype 1 subtype

Liver Biopsy (Metavir)

Baseline ALT (IU/L)

Baseline Viral Load*(log10copies/ml)

HCV RNA viral load decline (log10copies/ml)

SVR**

       

W2

W4

W8

W12

 

1

M

45

B

1

58

6.46

0.46

0.74

1.52

2.22

0

2

M

47

-

1

92

5.86

0.92

2.70

3.04

3.07

0

3

F

66

B

3

90

6.56

1.42

3.06

3.06

3.06

1

4

M

53

-

3

57

6.31

1.21

2.69

3.25

2.81

0

5

M

54

B

3

52

5.69

1.66

2.51

2.91

2.91

0

6

M

45

A

2

150

6.88

1.45

3.38

3.38

3.38

1

7

M

55

A

2

92

6.30

1.15

2.63

2.80

3.04

1

8

M

54

A

4

327

6.87

3.37

3.37

3.29

3.29

1

9

F

47

B

0

58

5.78

2.04

2.28

2.28

2.28

1

10

M

63

B

3

218

6.52

2.11

3.02

3.02

3.02

1

11

M

74

-

2

57

7.09

0.65

0.81

1.53

2.18

0

12

M

34

A

2

36

6.79

1.88

3.29

3.29

3.29

1

13

F

54

B

2

75

7.22

0.39

0.98

1.32

1.80

0

14

F

55

B

2

58

7.46

1.32

2.23

3.54

3.96

0

15

F

54

B

1

36

6.31

1.38

2.81

2.81

2.81

0

16

M

44

A

2

39

6.25

1.22

2.40

2.75

2.75

0

17

M

42

A

1

74

6.62

3.12

3.12

3.12

3.12

1

18

M

54

-

2

134

6.38

2.18

2.60

2.88

2.88

1

19

M

38

A

1

65

7.17

0.47

0.66

1.16

1.68

0

20

F

25

A

0

70

5.54

-0.08

0.64

2.04

2.04

0

  1. * Initial viral load Versant™ 3.0 HCV. ** Response, 6 months after the end of the treatment (0 = no response; 1 = response).