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Table 2 Diagnostic performance of HA in the validation set.

From: Accuracy of hyaluronic acid level for predicting liver fibrosis stages in patients with hepatitis C virus

HA cut-off Sensitivity (%) Specificity (%) NPV (%) PPV (%) Population involved (%) Interpretation
<16 91 36 82 55 24 Absence of fibrosis (F0F1) (82% certainty)
>121 14 99 57 94 7 Presence of fibrosis (F2) (94% certainty)
≤ 25 78 53 89 34 46 Absence of severe fibrosis (F0F1F2) (89% certainty)
>160 22 100 81 100 5 Presence of severe fibrosis (F3) (100% certainty)
≤ 50 100 79 100 20 75 Absence of cirrhosis (F0F1F2F3) (100% certainty)
>237 31 99 96 57 3 Presence of cirrhosis (F4) (57% certainty)
  1. Note 1: Accuracy = Sensitivity + Specificity + NPV + PPV. Note 2: Population involved stands for the proportion of patients who fall in the corresponding cut-off.