| |
Dose (mg Kg-1)
|
DT-diaphorase nmol/(min × mg protein)
|
EROD pmol/(min × mg protein)
|
Catalase mmol/(min × mg protein)
|
|---|
| | |
2 days
|
5 days
|
2 days
|
5 days
|
2 days
|
5 days
|
|---|
|
B(a)P
|
0
|
49.7 (9.4)
|
51.4 (20.3)
|
7.7 (3.7)
|
4.9 (1.5)
|
278 (52)
|
327 (33)
|
| |
5
|
58.3 (12.6)
|
59.4 (11.1)
|
159.3 (76.1)a
|
237.6 (146)a
|
334 (128)
|
398 (126)
|
| |
15
|
38.8 (16.1)
|
74.4 (15.8)ab
|
323.4 (280)a
|
491.8 (220)a
|
376 (96)
|
357 (114)
|
|
β-NF
|
0
|
50.5 (11.9)
|
54.0 (9.0)
|
8.5 (3.3)
|
7.7 (6.7)
|
297 (86)
|
247 (69)
|
| |
5
|
69.2 (16.3)
|
77.4 (19.8)
|
896.5 (156)a
|
943.3 (327)a
|
268 (93)
|
182 (75)
|
| |
15
|
72.1 (28.1)
|
101.7 (42.1)a
|
832.5 (399)a
|
877.3 (340)a
|
334 (131)
|
226 (95)
|
|
DHNQ
|
0
|
38.2 (5.3)
|
30.2 (7.6)
|
5.1 (3.2)
|
3.2 (1.8)
|
256 (103)
|
261 (171)
|
| |
1
|
45.3 (14.6)
|
40.4 (5.7)a
|
3.6 (1.9)
|
4.0 (3.9)
|
360 (132)
|
311 (152)
|
| |
3
|
41.7 (8.7)
|
48.3 (8.0)a
|
3.2 (1.6)
|
0.8 (0.5)ab
|
261 (69)
|
320 (64)
|
|
MN
|
0
|
40.7 (3.4)
|
47.0 (7.6)
|
7.3 (8.8)
|
10.0 (7.4)
|
144 (65)
|
204 (97)
|
| |
5
|
54.0 (9.4)a
|
65.0 (13.2)a
|
n.m.
|
6.6 (6.2)
|
136 (37)
|
215 (47)b
|
| |
15
|
35.7 (6.7)
|
51.8 (6.4)
|
5.5 (2.1)
|
5.2 (2.5)
|
127 (38)
|
158 (65)
|
|
PQ
|
0
|
47.2 (11.7)
|
46.9 (7.6)
|
5.5 (3.9)
|
2.2 (1.1)
|
245 (73)
|
248 (97)
|
| |
3
|
53.0 (8.3)
|
71.0 (6.0)a
|
4.3 (2.4)
|
1.4 (0.8)b
|
229 (47)
|
348 (55)ab
|
| |
10
|
43.7 (6.0)
|
61.8 (20.4)a
|
3.9 (1.1)
|
2.7 (1.3)
|
155 (23)a
|
171 (37)a
|
- Note: Values (n = 7) are presented as: mean (standard deviation); n.m. = not measured. aSignificantly different from control – p < 0.05; bSignificantly different from day 2 – p < 0.05.