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Table 1 Hepatic DT-diaphorase, EROD and catalase activities in rainbow trout exposed to benzo(a)pyrene (B(a)P), β-naphthoflavone (β-NF), naphthazarin (DHNQ), menadione (MN), or paraquat (PQ), for 2 and 5 days.

From: Effects of redox cycling compounds on DT diaphorase activity in the liver of rainbow trout (Oncorhynchus mykiss)

 

Dose (mg Kg-1)

DT-diaphorase nmol/(min × mg protein)

EROD pmol/(min × mg protein)

Catalase mmol/(min × mg protein)

  

2 days

5 days

2 days

5 days

2 days

5 days

B(a)P

0

49.7 (9.4)

51.4 (20.3)

7.7 (3.7)

4.9 (1.5)

278 (52)

327 (33)

 

5

58.3 (12.6)

59.4 (11.1)

159.3 (76.1)a

237.6 (146)a

334 (128)

398 (126)

 

15

38.8 (16.1)

74.4 (15.8)ab

323.4 (280)a

491.8 (220)a

376 (96)

357 (114)

β-NF

0

50.5 (11.9)

54.0 (9.0)

8.5 (3.3)

7.7 (6.7)

297 (86)

247 (69)

 

5

69.2 (16.3)

77.4 (19.8)

896.5 (156)a

943.3 (327)a

268 (93)

182 (75)

 

15

72.1 (28.1)

101.7 (42.1)a

832.5 (399)a

877.3 (340)a

334 (131)

226 (95)

DHNQ

0

38.2 (5.3)

30.2 (7.6)

5.1 (3.2)

3.2 (1.8)

256 (103)

261 (171)

 

1

45.3 (14.6)

40.4 (5.7)a

3.6 (1.9)

4.0 (3.9)

360 (132)

311 (152)

 

3

41.7 (8.7)

48.3 (8.0)a

3.2 (1.6)

0.8 (0.5)ab

261 (69)

320 (64)

MN

0

40.7 (3.4)

47.0 (7.6)

7.3 (8.8)

10.0 (7.4)

144 (65)

204 (97)

 

5

54.0 (9.4)a

65.0 (13.2)a

n.m.

6.6 (6.2)

136 (37)

215 (47)b

 

15

35.7 (6.7)

51.8 (6.4)

5.5 (2.1)

5.2 (2.5)

127 (38)

158 (65)

PQ

0

47.2 (11.7)

46.9 (7.6)

5.5 (3.9)

2.2 (1.1)

245 (73)

248 (97)

 

3

53.0 (8.3)

71.0 (6.0)a

4.3 (2.4)

1.4 (0.8)b

229 (47)

348 (55)ab

 

10

43.7 (6.0)

61.8 (20.4)a

3.9 (1.1)

2.7 (1.3)

155 (23)a

171 (37)a

  1. Note: Values (n = 7) are presented as: mean (standard deviation); n.m. = not measured. aSignificantly different from control – p < 0.05; bSignificantly different from day 2 – p < 0.05.