|
Treatment
|
Vitellogenin
|
17β-Estradiol
|
Testosterone
|
11-Keto-Testosterone
|
|---|
| |
(μg/ml plasma)
|
(pg/ml plasma)
|
(pg/ml plasma)
|
(pg/ml plasma)
|
|---|
| |
n = 7–8
|
n = 8
|
n = 7–8
|
n = 6–8
|
|---|
|
Vehicle (5 ml peanut oil/kg b.w.)
|
0.6 (1.0)
|
62 (56)
|
86 (68)
|
33 (38)
|
|
Ketoconazole (KC) (12 mg/kg b.w.)
|
0.6 (0.9)
|
60 (26)
|
120 (78)
|
71 (46)
|
|
Nonylphenol (NP) (25 mg/kg b.w.)
|
266 (199) a
|
76 (52)
|
75 (33)
|
42 (67)
|
|
Ethynylestradiol (5 mg/kg b.w.)
|
4,350 (1,463) a
|
100 (69)
|
90 (40)
|
35 (23)
|
|
KC + NP (12 + 25 mg/kg b.w.)
|
268 (205) a
|
36 (28)
|
61 (51)
|
36 (38)
|
- a Significantly different from vehicle treated fish (P < 0.001; Kruskal-Wallis ANOVA, followed by Mann-Whitney U-test). Each value represents the mean from 6–8 fish, followed by the SD, in brackets.
