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Figure 5 | Comparative Hepatology

Figure 5

From: Interactions between xenoestrogens and ketoconazole on hepatic CYP1A and CYP3A, in juvenile Atlantic cod (Gadus morhua)

Figure 5

Non-competitive inhibition of CYP1A by ethynylestradiol (A) and uncompetitive inhibition of CYP3A by ethynylestradiol (B). Dixon plots for ethynylestradiol on A) EROD activity (diamonds represent 8.2; squares represent 25 and triangles represents 677 pM ethoxyresorufin). B) BFCOD activity (diamonds represent 200; squares represent 267 and triangles represents 356 μM BFC).

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