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Figure 4 | Comparative Hepatology

Figure 4

From: Interactions between xenoestrogens and ketoconazole on hepatic CYP1A and CYP3A, in juvenile Atlantic cod (Gadus morhua)

Figure 4

Non-competitive inhibition of CYP1A by ketoconazole (A) and non-competitive inhibition of CYP3A by ketoconazole (B). Dixon plots for ketoconazole on A) EROD activity (diamonds represent 8.2; squares represent 25 and triangles represent 677 pM ethoxyresorufin). B) BFCOD activity (diamonds represent 48; squares represent 84 and triangles represent 200 μM BFC).

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