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Table 3 Values {Area under the ROC curves (AUROCs)} of SteatoTest, GGT and ALT for the diagnosis of steatosis greater than 5%, in both training and validation groups.

From: The diagnostic value of biomarkers (SteatoTest) for the prediction of liver steatosis

Diagnostic panel

Training Group AUROC (se)

Validation Group 1 – HCV before treatment

Validation Group 2 – HCV sustained responders

Validation Group 3 – Alcoholic liver disease

All groups

 

N = 310

N = 171

N = 201

N = 62

N = 884

SteatoTest

0.79 (0.03)*

0.80 (0.04)£

0.86 (0.03) $

0.72 (0.05)**

0.80 (0.02) ££

GGT

0.66 (0.03)

0.67 (0.05)

0.74 (0.05)

0.50 (0.09)

0.66 (0.02)

ALT

0.58 (0.03)

0.62 (0.05)

0.79 (0.04)

0.66 (0.07)

0.61 (0.02)

  1. * – Higher than GGT (P < 0.0001) and ALT (P < 0.0001); £ – Higher than GGT (P = 0.007) and ALT (P < 0.0001); $ – Higher than GGT (P = 0.02); ** – Higher than GGT (P = 0.002); ££ Higher than GGT (P < 0.0001) and ALT (P < 0.0001).