Skip to main content
Figure 4 | Comparative Hepatology

Figure 4

From: The establishment and characterization of the first canine hepatocellular carcinoma cell line, which resembles human oncogenic expression patterns

Figure 4

Mutation in the c-MET gene of cHCC (in figure as "c-MET cHCC") compared to healthy liver tissue (canine c-MET; Gen Bank accession number AB118945; "canine c-MET" in figure) and human c-MET (Gen Bank accession number NM_000245; "c-MET human" in figure) sequences. nt 4021–4219 of the canine c-MET is shown. The mutation is marked in grey at nt 4089 (A to T) of the canine c-MET, which corresponds to a change of amino acid 1363, from a threonine to a serine (T1363S). The STOP codon in the canine and human c-MET is also marked in grey. Alignment was performed by SECentral CLUSTAL W (1.7) multiple sequence alignment.

Back to article page

Comparative Hepatology

ISSN: 1476-5926