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Table 6 Summary of the diagnostic value of ActiTest for the differential diagnosis of all grades of necroinflammatory hepatic activity, according to the AUROCs.

From: Overview of the diagnostic value of biochemical markers of liver fibrosis (FibroTest, HCV FibroSure) and necrosis (ActiTest) in patients with chronic hepatitis C

  A0 A1 A2 A3 BD A0 A0A1 A1A2 A2A3
Blood Donor BD n = 300 0.67 0.84 0.96 0.99 - 0.79 0.89 0.97
A0 n = 185 -        
A1 n = 443 0.69 -       
A2 n = 370 0.87 0.70 -      
A3 n = 272 0.93 0.79 0.60 -     
A0A1 - - 0.70 0.83 -    
A1A2 0.77 - - 0.70 0.85 -   
A2A3 0.89 0.74 - - 0.94 0.78 -  
A0A1A2 - - - 0.75 - - - -
BD A0A1 - - 0.82 0.88 - - - 0.84
  1. The AUROCs between all different grade combinations are given. Between two contiguous grades (one-grade difference), the AUROCs are given in bold. Between patients with a two-grades difference, the AUROCs are given in italics. Between patients with a three-grades difference, the AUROCs are given in bold and italics. Between patients with a four- or five-grades difference (blood donors versus F3 or F4, and F0 versus F4), the AUROCs are underlined. Significant differences were observed between AUROCs when there was a two-grade or more difference.