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Table 5 Summary of the diagnostic value of FibroTest for the diagnosis of all stage combinations of hepatic fibrosis, according to the AUROCs.

From: Overview of the diagnostic value of biochemical markers of liver fibrosis (FibroTest, HCV FibroSure) and necrosis (ActiTest) in patients with chronic hepatitis C

  F0 F1 F2 F3 F4 BD F0 F0F1 F1F2 F2F3F4 F3F4
Blood Donor (BD) n = 300 0.71 0.86 0.95 0.99 0.99 - 0.84 0.88 0.97 0.99
F0 n = 95 -          
F1 n = 688 0.66 -         
F2 n = 253 0.82 0.69 -        
F3 n = 111 0.92 0.80 0.63 -       
F4 n = 123 0.95 0.87 0.75 0.65 -      
BD F0 0.71 0.81 0.92 0.98 0.98 -     
F0F1 - - 0.71 0.82 0.88 - - -   
F1F2 0.71 - 0.69 0.81 0.82 0.84 - - -  
F2F3 0.85 0.76 - - 0.72 0.92 0.80 - -  
F3F4 0.94 0.81 0.81 - - 0.98 0.89 0.80 -  
F2F3F4 0.83 0.78 - - - 0.95 0.78 - - -
BD F0F1 - - 0.77 0.87 0.91 - - - 0.83 0.89
  1. The AUROC between all different stage combinations are given. Between two contiguous stages (one- stage difference), the AUROCs are given in bold. Between patients with a two-stages difference, the AUROCs are given in italics. Between patients with a three-stages difference, the AUROCs are given in bold and italics. Between patients with a four- or five-stages difference (blood donors versus F3 or F4, and F0 versus F4), the AUROCs are underlined. Significant differences were observed between AUROCs when there was a two-stage or more difference.