Skip to main content

Table 3 Summary of the diagnostic value of ActiTest for the diagnosis of necroinflammatory hepatic activity (AUROC) in patients with chronic hepatitis C, from the published studies.

From: Overview of the diagnostic value of biochemical markers of liver fibrosis (FibroTest, HCV FibroSure) and necrosis (ActiTest) in patients with chronic hepatitis C

First author, Year Patient number Methodology Marker Grade/Prevalence AUROC (SE) Cut off Sensitivity Specificity
Imbert-Bismut, 2001 189 Prospective
Single center
ActiTest A2A3 / 0.33 0.79 (0.03) 0.10
0.30
0.60
0.80
0.99
0.91
0.70
0.49
0.07
0.42
0.75
0.88
Imbert-Bismut, 2001 134 Prospective
Single center
Validation cohort
ActiTest A2A3 / 0.28 0.75 (0.03) 0.10
0.30
0.60
0.80
1.00
0.94
0.67
0.42
0.07
0.33
0.65
0.87
Poynard, 2003 352 Retrospective
Randomized trial
Multicenter
Before treatment
ActiTest A2A3 / 0.83 0.75 (0.03) 0.10
0.30
0.60
0.80
1.00
0.90
0.49
0.20
0.00
0.38
0.87
0.99
Poynard, 2003 352 Retrospective
Randomized trial
Multicenter
After treatment
ActiTest A2A3 / 0.39 0.86 (0.02) 0.10
0.30
0.60
0.80
0.91
0.75
0.38
0.14
0.59
0.83
0.98
0.996