Figure 2

Diagnostic values of FibroTest according to genotype and viral load. Graph A: AUROCs of FibroTest for the diagnosis of significant fibrosis, according to HCV genotypes. There were no significant differences: Genotype 1, n = 684, AUROC = 0.76, 95% Confidence Interval (95CI) = 0.72–0.79; genotype 2, n = 140, AUROC = 0.79, 95CI = 0.70–0.85; genotype 3, n = 143 AUROC = 0.76, 95CI = 0.67–0.83; other genotype, n = 46, AUROC = 0.72, 95CI = 0.52–0.85. Graph B: AUROCs of ActiTest for the diagnosis of significant necrosis, according to HCV genotypes. There were no significant differences: Genotype 1, n = 684, AUROC = 0.81, 95% Confidence Interval (95CI) = 0.77–0.84; genotype 2, n = 140, AUROC = 0.90, 95CI = 0.83–0.94; genotype 3, n = 143, AUROC = 0.79, 95CI = 0.71–0.85; other genotype, n = 46, AUROC = 0.76, 95CI = 0.57–0.87. Graph C: AUROCs of FibroTest for the diagnosis of significant fibrosis, according to serum HCV viral load. There were no significant differences: High viral load, n = 215, AUROC = 0.71, 95% Confidence Interval (95CI) = 0.64–0.78; Low viral load, n = 183, AUROC = 0.73, 95CI = 0.65–0.80. Graph D: AUROCs of ActiTest for the diagnosis of significant necrosis, according to serum HCV viral load. There were no significant differences: High viral load, n = 215, AUROC = 0.74, 95% Confidence Interval (95CI) = 0.64–0.82; Low viral load, n = 183, AUROC = 0.75, 95CI = 0.65–0.82.