Table 1 Plasma levels of investigated parameters of Sprague-Dawley rats after in vivo treatment with nitric oxide donor (SNP) and peroxynitrite. Data expressed as Mean (SD); n = 8 per group.
From: Sodium nitroprusside and peroxynitrite effect on hepatic DNases: an in vitro and in vivostudy
Parameters | Control | SNP | Peroxynitrite |
|---|---|---|---|
Lipid peroxidation (MDA) (μmol/l) | 7.10 (0.86) | 6.78 (2.11) | 6.64 (2.85) |
SH groups (μmol/l) | 180.47 (36.08) | 150.84 (4.78) | 110.40 (11.96)* |
NO2+NO3 (μmol/l) | 45.47 (18.80) | 66.82 (4.12) | 81.94 (10.18) |
Uric acid (μmol/l) | 64.82 (4.18) | 22.34 (8.32) | 17.50 (3.21)* |
Carbonyl groups (μmol/g protein) | 179.59 (28.50) | 144.90 (67.40) | 169.06 (14.88) |
Nitrotyrosine (nmol/g protein) | 96.02 (26.53) | 136.17 (27.47) | 135.11 (4.64) |
ALT (U/l) | 31.9 (4.15) | 34.44 (4.96) | 28.5 (5.15) |