Distribution of keratin IFs and K8 pS436 in hepatocytes from control and GF-fed C3H mice. A, C, E, G keratin IFs; B, D, F, H K8 pS436; A, B) control; C, D) 2 week treatment; E, F) 6 week treatment; G, H); 5 month treatment. Arrows in D indicate clusters of cells containing K8 pS436. Filled arrowheads in G and H indicate reactive MBs with Troma 1 and 5B3 (anti-K8 pS436), respectively. Scale bar = 20 μm.