Figure 1

Receptor specificity. Specificity of uptake of ¹²⁵I-AGG (A), ¹²⁵I-FSA (B), ¹²⁵I-collagen (C), ¹²⁵I-mannan (D), or ¹²⁵I-FITC-bHA (E) in LSEC in the presence of mannose (50 mM), FSA (0.1 mg/ml), COLLA (0.1 mg/ml), hyaluronan (0.1 mg/ml) and AGG (0.3 mg/ml). Uptake (cell-associated radioactivity (solid bars) plus acid soluble radioactivity in spent medium [open bars]) was measured after 120 min incubation at 37°C. Results, given as % of control, are means of three experiments, each consisting of three parallels. Error bars represent standard deviation (+SD).