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Table 2 Inter and intra-individual variability of FibroTest and ActiTest components and two positive controls (glucose and triglycerides) according to fasting

From: Intra-individual fasting versuspostprandial variation of biochemical markers of liver fibrosis (FibroTest) and activity (ActiTest)

  A2M g/L HPT g/L APOA1 g/L BT μmol/L GGT U/L ALT U/L FibroTest ActiTest Glucose Triglycerides
Mean (SD)           
   Fasting 1.98 (0.67) 0.95 (0.55) 1.40 (0.46) 21 (25) 90 (127) 48 (47) 0.36 (0.33) 0.27 (0.25) 5.09 (2.43) 1.38 (1.97)
   Postprandial 1.99 (0.64) 0.96 (0.53) 1.40 (0.46) 21 (24) 88 (123) 47 (42) 0.36 (0.33) 0.27 (0.25) 6.17 (3.15) 1.88 (1.94)
Spearman Coefficient 0.96 0.98 0.94 0.87 0.995 0.98 0.98 0.98 0.45 0.75
ANOVA p value 0.92 0.93 0.98 0.99 0.98 0.94 0.98 0.94 0.04 0.01
Coefficient of Variation (log)*           
   Inter-individual Fasting 0.34 (0.50) 0.58 (-2.85) 0.33 1.17 (0.28) 1.41 (0.30) 0.98 (0.23) 0.91 0.27 0.48 1.43
   Inter-individual Postprandial 0.32 (0.48) 0.55 (-2.93) 0.33 1.15 (0.29) 1.40 (0.30) 0.90 (0.22) 0.90 0.27 0.51 1.03
   Intra-individual Regression ** 0.10 (0.14) 0.13 (-0.41) 0.09 0.25 (0.10) 0.14 (0.02) 0.18 (0.04) 0.09 0.13 0.31 0.65
  1. Data are quoted for all 64 subjects. * As all components except apolipoprotein A1 are computed using the logarithmic transformation in FibroTest and ActiTest formulas, the coefficient of variation was also assessed in log for these five components. ** Represents the intra-individual variability of the linear regression between fasting and postprandial values.