Figure 2

Membrane associated plasminogen activator activity (nmol/min/mg protein) in the group for whom the estimated resection size was 50% or greater and for the group where the resection size was less than 50%. Samples were: Start (control sample taken at start of operation); 1 = Res 0; 2 = Rem 0; 3 = Res End; and 4 = Rem End; as described in the Methods. Values are means and the error bars are 95% confidence limits. For the 50% and greater group (Figure 2A), Student's paired t test analysis showed the Start and Rem End samples to be statistically significantly different (p = 0.002, n = 8). There were no statistical differences between start and any of the other samples. For the less than 50% group (Figure 2B), there were no statistical differences between any of the samples (n = 10). The relationship between increased uPA activity in the Rem End samples and extent of resection is shown in Figure 2C. There was no statistical correlation below 50% resection (Spearman correlation coefficient = -0.22, p = 0.268) but for 50% resection and higher a positive statistical correlation was observed (Spearman correlation coefficient = 0.67, p = 0.025, n = 9)