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Figure 4 | Comparative Hepatology

Figure 4

From: Expression of leukemia inhibitory factor (LIF) and its receptor gp190 in human liver and in cultured human liver myofibroblasts. Cloning of new isoforms of LIF mRNA

Figure 4

Regulation of LIF secretion by interleukin-4. Confluent cultures of human liver myofibroblasts were cultured in the presence of the indicated concentrations of IL-4, for 48 h in serum-free medium. LIF was measured by ELISA in the supernatant and the results were normalized according to the DNA content of the monolayer (mean ± SD of 3 experiments). The effect of IL-4 was highly significant, as assessed by ANOVA (p = 0.001).

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