Figure 4From: Expression of leukemia inhibitory factor (LIF) and its receptor gp190 in human liver and in cultured human liver myofibroblasts. Cloning of new isoforms of LIF mRNARegulation of LIF secretion by interleukin-4. Confluent cultures of human liver myofibroblasts were cultured in the presence of the indicated concentrations of IL-4, for 48 h in serum-free medium. LIF was measured by ELISA in the supernatant and the results were normalized according to the DNA content of the monolayer (mean ± SD of 3 experiments). The effect of IL-4 was highly significant, as assessed by ANOVA (p = 0.001).Back to article page