Figure 1

Hepatic NK cells induce apoptosis in P815 cells as shown by TEM. P815, P815 cells in medium only; P815+H-NK, P815 cells coincubated for 3 h with hepatic NK cells at an E/T ratio of 10/1. When P815 cells are coincubated with hepatic NK cells (thin arrow), nuclei of P815 cells become condensed and fragmented (thick arrow). Note the granules present in the hepatic NK cells (arrowhead). Bar: 1 –m. (From reference 8, with permission.)