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Table 6 Effect of thalidomide and TNF-alpha on LPS-induced TNF-alpha production by cultured Kupffer cells.

From: Thalidomide Prevents Alcoholic Liver Injury in Rats Through Inhibition of Kupffer Cell Sensitization

 

TNF-alpha (pg/ml)

LPS (100 ng/ml)

726 – 82

TNF-alpha (10 ng/ml)+ LPS

936 – 186*

Thalidomide (5 micromolar) + TNF-alpha + LPS

439 – 105**

  1. * p < 0.05 vs. TNF-alpha(-), ** p < 0.05 vs. TNF-alpha(+).