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Figure 2 | Comparative Hepatology

Figure 2

From: Kupffer cells promote lead nitrate-induced hepatocyte apoptosis via oxidative stress

Figure 2

Light micrographs of rat liver sections (a,c) from control animals and (b,d) three days after a single GdCl3 injection; (a, b) toluidine blue staining and (c, d) unstained sections of livers of GdCl3-treated rats. In normal livers large Kupffer cells, lining liver sinusoids are indicated by arrows(a) or evidenced by the colloidal carbon particles uptaken by Kupffer cells (c) (arrowheads); b) three days after GdCl3 administration; the majority of large Kupffer cells disappeared from liver and (d) the phagocytic activity is depressed as the scarce internalization of carbon shows (arrowhead). The asterisk (b) indicates a hepatocyte in mitosis. Bar = 10 μm.

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