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Figure 1 | Comparative Hepatology

Figure 1

From: Eggshell and egg yolk proteins in fish: hepatic proteins for the next generation: oogenetic, population, and evolutionary implications of endocrine disruption

Figure 1

Schematic representation of the hypothalamus-pituitary-gonadal-liver (HPGL) axis during oogenic protein synthesis in female teleosts. The HPGL is regulated through the negative feedback mechanism by estradiol-17β. The hypothamalus, pituitary, gonad and liver are all potential targets for endocrine disruptors, as discussed in the text. GtH = gonadotropin I & II.

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