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Table 2 Genes proposed to regulate angiogenesis with specific functions according to Ace View[46]

From: The genetic regulation of the terminating phase of liver regeneration

Resection Group Up-regulated Down-regulated Function
3-0 weeks FGF9 (0.3)   Involved in cell growth
   VEGFA (−0,7) Inducing angiogenesis, vasculogenesis and endothelial cell growth
6-0 weeks EDG1 (0,3)   Regulate differentiation of endothelial cells
   VASH2 (−0,4) Positive regulation of angiogenesis and endothelial cell proliferation
6-3 weeks ANGPTL2 (0,3)   Growth factor specific for vascular endothelium
  FGF20 (0,4)   Involved in cell growth
   VASH2 (−0,3) Positive regulation of angiogenesis and endothelial cell proliferation
Sham Group    
3-0 weeks ANGPTL3 (0,2)   Growth factor specific for vascular endothelium
   ANGPT2 (−0,2) Negative regulation of angiogenesis by inducing endothelial cell apoptosis
6-0 weeks FAP (0,2)   Involved in control of fibroblast growth
  FGF9 (0,3)   Involved in cell growth
  FGFBP3 (0,3)   Positive regulation of fibroblast growth factor
  VEZF1 (0,8)   Participates in angiogenesis
6-3 weeks VEZF1 (1,0)   Involved in angiogenesis
  VEZF1 (0,7)   Involved in angiogenesis
   AMOTL2 (−0,2) Angiomotin binds angiostatin, an inhibitor of angiogenesis
   FGFR1OP (−0,2) Involved in angiogenesis and cell growth
Control Group    
3-0 weeks AMOTL1 (0,4)   Angiomotin binds angiostatin, an inhibitor of angiogenesis
   FGF8 (−0,6) Involved in cell growth
6-0 weeks AMOTL1 (0,7)   Angiomotin binds angiostatin, an inhibitor of angiogenesis
  FGF20 (0,4)   Involved in cell growth
   FGFR3 (−0,2) Involved in cell growth
6-3 weeks FGF8 (0,4)   Overexpression has been shown to increase tumor growth and angiogenesis
   VEZF1 (−0,9) Involved in angiogenesis