Severe diabetes and leptin resistance cause differential hepatic and renal transporter expression in mice

Comparative Hepatology

Table 1 Body, liver and kidney weight and blood glucose levels for db/db and C57BKS control mice ^a

Strain	Gender	Liver Weight (g)	Kidney weight (g)	Average body weight (g)	Liver/Body weight	Mean blood glucose levels (mg/dL)
C57BKS	Female	0.89 ± 0.03	0.25 ± 0.00	17.75 ± 0.23	0.050 ± 0.001	156 ± 3
	Male	1.00 ± 0.02	0.31 ± 0.02	21.89 ± 0.35	0.046 ± 0.001	158 ± 9
Db/db	Female	1.88 ± 0.08*	0.28 ± 0.01	37.71 ± 0.60*	0.050 ± 0.001	442 ± 48*
	Male	1.87 ± 0.06*	0.33 ± 0.01	38.67 ± 0.44*	0.048 ± 0.001	455 ± 33*

^aLivers, kidneys, and blood were collected from C57BKS and db/db mice at 9 weeks of age. (*) indicates values significantly different from control (p ≤ 0.05). All weights expressed in grams ± SEM. Asterisk (*) represents statistically significant difference of parameters between C57BKS and db/db mice (p≤0.05).