TY - JOUR AU - Sökmen, Hacı Mehmet AU - Özdil, Kamil AU - Çalhan, Turan AU - Şahin, Abdurrahman AU - Şenateş, Ebubekir AU - Kahraman, Resul AU - Niğdelioğlu, Adil AU - Zemheri, Ebru PY - 2011 DA - 2011/08/03 TI - Situs inversus totalis and secondary biliary cirrhosis: a case report JO - Comparative Hepatology SP - 5 VL - 10 IS - 1 AB - Situs inversus totalis is is a congenital anomaly associated with various visceral abnormalities, but there is no data about the relationship between secondary biliary cirrhosis and that condition. We here present a case of a 58 year-old female with situs inversus totalis who was admitted to our clinic with extrahepatic cholestasis. After excluding all potential causes of biliary cirrhosis, secondary biliary cirrhosis was diagnosed based on the patient's history, imaging techniques, clinical and laboratory findings, besides histolopathological findings. After treatment with tauroursodeoxycholic acid, all biochemical parameters, including total/direct bilirubin, alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase and gama glutamyl transferase, returned to normal ranges at the second month of the treatment. We think that this is the first case in literature that may indicate the development of secondary biliary cirrhosis in a patient with situs inversus totalis. In conclusion, situs inversus should be considered as a rare cause of biliary cirrhosis in patients with situs inversus totalis which is presented with extrahepatic cholestasis. SN - 1476-5926 UR - https://doi.org/10.1186/1476-5926-10-5 DO - 10.1186/1476-5926-10-5 ID - Sökmen2011 ER -