From: Characterization of chronic HCV infection-induced apoptosis
Variable N = 35 (%) |
Bak N = 24 (%) |
Fas N = 19 (%) |
FasL N = 8 (%) |
Bcl-2 N = 28 (%) |
Bcl-xL N = 9 (%) |
---|---|---|---|---|---|
Age (mean ± SD) | |||||
57 ± 10.2 | |||||
≤ 55: 16 (46) | 12 (75) | 7 (44) | 3 (19) | 10 (63) | 5 (31) |
> 55: 19 (54) | 12 (63) | 12 (63) # | 5 (26) | 18 (95) # | 4 (21) |
Gender | |||||
M: 22 (63) | 17 (77) # | 12 (55) | 5 (23) | 19 (86) # | 4 (18) |
F: 13 (37) | 7 (54) | 7 (54) | 3 (23) | 9 (69) | 5 (38) # |
Tumor size | |||||
≤ 8: (22) | 14 (64) | 10 (45) | 4 (18) | 17 (77) | 5 (23) |
> 8: (13) | 10 (77) | 9 (69) | 5 (38) | 9 (69) | 4 (31) |
Grade | |||||
II: 22 (63) | 16 (73) # | 10 (45) | 4 (18) | 17 (77) | 6 (27) |
III: 13 (37) | 8 (61) | 9 (69) # | 4 (31) | 11 (84) # | 3(23) |
Invasion | |||||
Positive: (18) | 15 (83) # | 12 (67) | 6 (33) | 15 (83) | 6 (33) |
Negative: (17) | 9 (53) | 7 (41) | 2 (12) | 13 (76) | 3 (18) |
Cirrhosis | |||||
Present: 15 (43) | 8 (53) | 10 (67) # | 4 (27) | 12 (80%) | 3 (20) |
Absent: 20 (57) | 16(80) # | 9 (45) | 4 (20) | 16 (80%) | 6 (30) |