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Table 4 NASH scoring of H&E stained liver sections and fibrosis scores in Sirius Red stained liver sections

From: The effect of cocoa supplementation on hepatic steatosis, reactive oxygen species and LFABP in a rat model of NASH

  Score MCS
(% of cases)
MCD
(% of cases)
C1
(% of cases)
C2
(% of cases)
C3
(% of cases)
C4
(% of cases)
Steatosis 0 100% 0% 0% 0% 0% 0%
  1 0% 13% 0% 0% 31% 12%
  2 0% 17% 0% 0% 50% 19%
  3 0% 70% 100% 100% 19% 69%
Significant   MCD, C1, C2, C3, C4 MCS, C3 MCS, C3 MCS, C3 MCS, MCD, C1, C2 MCS
Portal inflammation 0 88% 83% 69% 21% 94% 94%
  1 12% 17% 31% 79% 6% 6%
Significant   C2 C2 C2 MCS, MCD, C1, C3, C4 C2 C2
Lobular inflammation 0 27% 8% 0% 0% 19% 0%
  1 67% 4% 13% 13% 31% 31%
  2 2% 57% 64% 64% 50% 56%
  3 4% 31% 23% 23% 0% 13%
Significant   MCD, C2 MCS N/S MCS N/S N/S
Fibrosis 0 12.5% 0% 0% 0% 0% 0%
  1A 0% 18.8% 0% 0% 0% 0%
  1B 87.5% 62.5% 12.5% 14.3% 62.5% 37.5%
  1C 0% 0% 0% 0% 0% 0%
  2 0% 6.3% 62.5% 0% 37.5% 50%
  3 0% 12.5% 25% 85.7% 0% 12.5%
  4 0% 0% 0% 0% 0% 0%
Significant   MCD, C1, C2, C3, C4 MCS, C1, C2, C3, C4 MCS, MCD, C2, C3, C4 MCS, MCD, C1, C3, C4 MCS, MCD, C1, C2, C4 MCS, MCD, C1, C2, C3
  1. Steatosis (0-3), portal inflammation (0-1), lobular inflammation (0-3) and fibrosis (0-4). Groups that are significantly different are listed below values, p < 0.05.