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Figure 4 | Comparative Hepatology

Figure 4

From: MHC class I expression protects rat colon carcinoma cells from hepatic natural killer cell-mediated apoptosis and cytolysis, by blocking the perforin/granzyme pathway

Figure 4

Effect of the pan caspase inhibitor Z-VAD-FMK on anti-MHC I mAb OX18 enhanced cytolysis (A, 51Cr release) and apoptosis (B, DNA fragmentation). Z-VAD-FMK was present during coincubation. CC531s cells were incubated at an E:T ratio of 10:1 with hepatic NK cells for 18 h (51Cr release) or 3 h (DNA fragmentation). **p < 0.01 vs. the corresponding control (LSD test).

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Comparative Hepatology

ISSN: 1476-5926