Figure 3
Conversion between FibroTest and fibrosis stages, and between ActiTest and necroinflammatory activity grades – Graphs. Graph A: FibroTest values according to status, from blood donors to patients with cirrhosis (n = 1570). Graph B: ActiTest values according to status, from blood donors to patients with severe necrosis (n = 1570). F0 = no fibrosis, F1 = portal fibrosis, F2 = some septa, F3 = many septa, F4 = cirrhosis, A0 = no necroinflammatory activity, A1 = minimal activity, A2 = moderate activity, A3 = severe activity. (Consensus conferences recommend treatment in patients with either F2 stage or A2 grade.) Notched box plots showing the relationship between FibroTest and the stage of fibrosis (A) and between ActiTest and the grade of activity (B). The horizontal line inside each box represents the median, and the width of each box the median ± 1.57 interquartile range/√n (to assess the 95% level of significance between group medians). Failure of the shaded boxes to overlap signifies statistical significance (P < 0.05). The horizontal lines above and below each box encompass the interquartile range (from 25th to 75th percentile), and the vertical lines from the ends of the box encompass the adjacent values (upper: 75th percentile plus 1.5 times interquartile range, lower 25th percentile minus 1.5 times interquartile range).